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When to Seek Emergency Medical Care Seek immediate emergency care if you develop severe abdominal pain that does not improve with rest, persistent vomiting lasting more than 4 to 6 hours, signs of pancreatitis (upper-left abdominal pain radiating to your back), severe dehydration unresponsive to oral fluids, or difficulty breathing

This combination is not suitable if you have hyperthyroidism, because both Phentermine and hyperthyroidism increase catecholamine (adrenaline) levels in your body, which can worsen symptoms like rapid heart rate, hypertension, anxiety, and weight loss

While 68 weeks provides a reasonably strong safety profile, it does not answer questions about what happens over 3, 5, or 10 years of continuous use

After a dose increase: Any time your doctor increases your dose, nausea can temporarily return as your system adapts to the higher level of medication

Not significantly

Huerta et al
