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Curr Diabetes Rev 19:3145 Gejl M, Gjedde A, Egefjord L et al (2016) In Alzheimers disease, 6-month treatment with GLP-1 analog prevents decline of brain glucose metabolism: randomized, placebo-controlled, double-blind clinical trial

Whether GLP-1R is expressed in endothelial cells remains controversial 28,33,34,35

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The starting dose considerations from your tirzepatide experience still inform your approach, but conservatism serves you well here

Support may include: Reviewing current medications and medical history

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