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[4] [5] For weight management, NICE technology appraisals (TA875 for Wegovy, TA664 for Saxenda) specify these treatments should be used within specialist weight management services (tier 3 or 4), with specific eligibility criteria, time-limited use, and defined stopping rules

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A slower titration often means gentler symptoms

Risk differences were higher in men, patients aged 50 years or older, and those with cardiovascular disease or ophthalmic conditions, with minimal differences in women and those younger than 50 years

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Most mainstream protein bars contain sugar alcohols, artificial sweeteners, and fiber additives that trigger nausea when combined with GLP-1s delayed gastric emptying