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8 In CY-5 experiments, if Ser 16 from GCG was changed to Lys from GIP, the GLP-1 activity decreased while the GIP activity increased

Clayton Frenzel, triple board-certified and dual fellowship-trained prescribes and manages tirzepatide as part of a medically supervised weight loss program

When initiating or escalating tirzepatide, doses of insulin or sulfonylureas should be reduced to minimize hypoglycemia risk

These drugs have demonstrated impressive weight loss results in clinical trials

Many patients use phone reminders or medication logs to prevent accidental use of expired doses