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When used in combination with lifestyle modifications, GLP-1 agonists can result in significant reductions in body weight, along with improvements in related conditions such as high blood pressure, high cholesterol, and type 2 diabetes
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Still, the research cited post-usage boomerangs and found that 50% of previous users are likely to use these drugs again

Nonetheless, since mediation analyses rely on strong assumptions, these findings should be interpreted with caution, and causal inferences regarding the exact contribution of weight-independent pathways cannot be definitively established

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