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This produces a myriad of effects on metabolism pathways: Pancreatic and glycemic control [edit] Semaglutide enhances the growth and proliferation of pancreatic beta cells, which are responsible for insulin production, while mitigating oxidative stress to reduce cell death (apoptosis)

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Patients prescribed Ozempic should be aware that the most frequently reported adverse effects involve the gastrointestinal system, such as nausea, vomiting, and diarrhoea

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It is highly expressed in the hypothalamus, where it plays a crucial role in the regulation of protein trafficking and recycling, which affect secretory granule biogenesis ( MAGEL2 cause Schaaf-Yang syndrome (MIM: 615547), which is characterized by delayed psychomotor development, frequent intellectual disability, hypotonia, feeding difficulties, and various dysmorphic facial features