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Both are injected once weekly using pre-filled pens, come in escalating dose strengths (2.5 mg to 15 mg), and are manufactured under FDA Current Good Manufacturing Practice (CGMP) standards

Basic math, more water in means more water out

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Hympavzi, which was simultaneously authorized for the treatment of hemophilia A, is also the first treatment available through a pre-filled pen or syringe for either condition, according to Pfizer

Even a modest 5 mg dose requires 200 units, which is 2 mL of liquid and two full syringe draws