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In the AD line, Donanemab announced phase 3 clinical results and re-submitted BLA, other notable developments include the next generation BTK inhibitor Pirtobrutinib results from phase 1/phase 2 CLL trials, IL23p19 monoclonal antibody Mirikizumab's approval in Europe, and PD-1 monoclonal antibody Peresolimab's first-time results of RA indication

doi: 10.5414/cpp46273

#3 Exploiting consumer interest in resistant starch, prebiotic fibers and other ingredients that naturally boost satiety either by stimulating gut hormones such as GLP-1 or via other mechanisms

Each additional receptor target adds complexity to the side effect profile, the dose-response relationship, and the long-term safety considerations

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