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Peak-to-trough ratio drops by approximately 30-40%

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Mounjaro and Zepbound are given as subcutaneous injections
In addition to regulating metabolism, strong cardiovascular and renal outcome trial data (including STEP, SELECT, and FLOW) suggest that they can lower the disease burden of serious cardiovascular events and protect kidney functioning

However, our exclusion of patients with pre-existing vestibular diagnoses mitigates this concern

The most important effect of GLP-1 is to increase insulin secretion after a meal, and this effect is dependent on glucose concentration, so despite promoting insulin secretion, the occurrence of hypoglycemia is rare [25]