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Description
The effects of GLP-1 are mediated through its binding to the GLP-1 receptor (GLP1R)
Those used for diabetes require individual benefit-risk assessment in pregnancy
Additionally, the proximity of the rectum to the urethra (particularly in women) means that prolonged constipation increases the bacterial load near the urinary opening
Because these products are often mismeasured or misusedwith doses taken more frequently or in higher amounts than recommendedthey can cause adverse events such as nausea, vomiting, diarrhea, abdominal pain, constipation, or more severe outcomes like hospitalization and pancreatitis
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