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In humans, there are three PPAR PPAR, PPAR/, and PPAR isoforms that are encoded by distinct genes and are expressed in different ways in organs and tissues

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Most common side effect: Nausea (15%-20% of patients, depending on dosage)

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This water is excreted as the glycogen depletes, which is why many people experience noticeably increased urination in the first week or two of treatment and lose what appears to be a significant amount of weight very quickly