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Additional exclusion considerations in clinical research design: Severe renal impairment (eGFR below 30 mL/min/1.73m2)

Participants receiving liraglutide demonstrated a reduction in binge eating days per week compared to placebo, alongside modest weight loss

It is an oral formulation of semaglutide, making it easier to administer

Scientists now understand that beneficial bacteria help produce compounds called short-chain fatty acids (SCFAs), including butyrate, which play major roles in insulin sensitivity, satiety signaling, gut barrier integrity, and metabolic flexibility

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As compounding pharmacies continue to develop around additive combinations, pharmaceutical stakeholders must closely monitor the clinical and regulatory implications