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daily liraglutide on body weight in adults with overweight or obesity without diabetes: The STEP 8 randomized clinical trial

The effectiveness of once-daily subcutaneous liraglutide administration for weight loss management in adults was established in five large-scale randomized multicentre phase 3 trials [49,50,51,52,53], four of which were part of the SCALE program (Satiety and Clinical AdiposityLiraglutide Evidence in nondiabetic and diabetic individuals), leading to its approval at a dose of 3.0 mg subcutaneous once-daily (weekly increased from 0.6 mg to 3 mg/day)
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Endocrinology and Diabetes, 15, 19

Hazard ratios and 95% CIs (shaded areas) according to ACR (B, D) adjusted for each other, age, sex, ethnic origin, history of cardiovascular disease, systolic BP, diabetes, smoking, and total cholesterol
