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Chronic migraine is defined as having 15 or more headache days per month over three months, with at least eight days showing migraine features like aura, nausea, or light and sound sensitivity

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These individuals may have already tried lifestyle modifications, including dietary changes and increased physical activity, but have not achieved the desired results

However, elucidation of mechanisms controlling glp-1 transcription has been lacking

Krogh and Hagedorn are consulting on it

In addition to GLP-1 medications, there are also tirzepatide-based medications, which are both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists