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Each injection requires a fresh needle to maintain sterility and prevent infection, tissue damage, and medication degradation

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In 2014, the Stimulation Therapy for Apnea Reduction (STAR) trial found that, among patients with moderate-to-severe OSA and a body mass index (BMI) of less than 32 kg/m 2 , unilateral hypoglossal nerve stimulation led to a 68% reduction in OSA severity (based on AHI) at 12 months, and improvements in sleepiness scores [44]