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For example, exendin-4 inhibited the generation of the adhesion molecule ICAM-1 in these endothelial cells, and this effect could be blocked by a GLP-1 receptor antagonist (57)

Reduced glucose metabolism in AD may be a consequence of reduced postsynaptic neurotransmission, since depolarizing agents trigger glucose uptake in the brain and the effect is reduced in AD (60)

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Bunck MC, Diamant M, Corner A, Eliasson B, Malloy JL, Shaginian RM, Deng W, Kendall DM, Taskinen MR, Smith U, Yki-Jarvinen H, Heine RJ

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