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The second is that the study looked exclusively at people with diabetes, as theyre at a higher risk of developing mental health disorders making it unclear if these potential benefits would apply to people taking GLP-1s for other reasons

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To be clear, the only FDA-approved manufacturers of these medications are the companies that created the active pharmaceutical ingredients Novo Nordisk and Eli Lilly, the joint statement read

Adherence rates varied by product, with members significantly more adherent to semaglutide (Ozempic) and dulaglutide (Trulicity) than to other products

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The conjugate research and much of the mechanistic work described here remains preclinical, conducted in animal models and cell systems rather than in human clinical trials