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RELEVANCE: Older adults are at higher risk of frailty, sarcopenia, dehydration, and nutritional decline

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A study in Nature found a specific genetic variant that may boost the effectiveness of GLP-1 weight-loss drugs like semaglutide and tirzepatide.

GLP-1 injections and CoolSculpting are popular treatments for weight and fat loss

While generally well-tolerated, GLP-1 RAs can be associated with adverse events, including pancreatitis, acute kidney injury (AKI), gastroparesis, nausea, diarrhea, abdominal pain, and decreased appetite

Because the patient has not yet been approved, the claim would be expected to reject or deny