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95% CI 0.95- 1.12) (210)
190 Initially, GLP-1 secretion by L-cells was believed to occur in a glucose-dependent manner
Tirzepatide is a dual agonist targeting both GLP-1 and GIP receptors, improving insulin sensitivity and promoting fullness, leading to superior weight losssome patients lose over 20%, with an average of 15%
Hyponatremia (low sodium) can develop through multiple mechanisms: excessive fluid intake relative to sodium (dilutional) or gastrointestinal sodium losses
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concerns are similar to those reported in adults
