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Metabolism Open

[DOI] [PMC free article] [PubMed] [Google Scholar] 171.Garvey W.T., Mechanick J.I., Brett E.M., Garber A.J., Hurley D.L., Jastreboff A.M., Nadolsky K., Pessah-Pollack R., Plodkowski R., Reviewers of the AACEOCPG American Association of Clinical Endocrinologists and American College of endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity

Tirzepatide Shows Neuroprotective Effects via Regulating Brain Glucose Metabolism in APP/PS1 Mice

However, a troubling signal emerged suggesting a possible raised risk for heart failure, though the endpoint was not rigorously studied in the trials

These results support the rationale of developing retatrutide as an alternative to semaglutide and/or tirzepatide 5