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[1] The most frequently reported adverse effects of semaglutide include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, constipation, and abdominal pain

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Exendin-4 is a 39 amino acid peptide with 53% identity to GLP-1 (34) and is fully active at GLP-1 receptors and not degraded by DPP-4