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Given our current understanding that DHEAS acts as a GABA A receptor antagonist, it is unclear how blocking the GABA A receptor channel blocked the neuroprotective effect of DHEAS

Thats a sign to reassess

Buczyska et al., 2021

Evaluation and Treatment of Adult Growth Hormone Deficiency: An Endocrine Society Clinical Practice Guideline

Although no cognitive differences were found between the studied groups after liraglutide treatment, the GLP-1 receptor agonist could improve connectivity between bilateral hippocampal areas and the brain anterior medial frontal structures of the treated patients
Some patients report a significant decrease in their alcohol cravings, while others find that they become more sensitive to the effects of alcohol, leading to reduced consumption
