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Ablation of AT1A receptors specifically in the LepR-expressing neurons diminishes the RMR in response to a high-fat diet or deoxycorticosterone acetate-salt treatments [181, 182]

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Luzzi V, Mazur M, Guaragna M, et al
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It reduces the risk of significant Cardiovascular events, which include heart attack, stroke, and cardiovascular death, in people with type 2 Diabetes Mellitus, in those with established heart disease, and in those with multiple cardiovascular risk factors
