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As a peptide-based molecule, it would be broken down by digestive enzymes before reaching the bloodstream in any meaningful quantity

Generally considered safe when taken in recommended doses

Thus, several studies have demonstrated the presence of prohormone convertase 1/3 [PC1/3, the processing enzyme that cleaves proglucagon to generate GLP-1 (105)] and fully processed GLP-1 in rodent and human -cells and islets in culture (106110), and GLP-1 can be detected in the media, suggesting that it is secreted from the -cells

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Genotypes are: (B) lst-1(ok814)

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