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Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes2019

Its seven-day half-life enables once-weekly dosing, and it reaches steady state at any given dose in approximately four to five weeks

In addition, a head-to-head trial of semaglutide and liraglutide was conducted in the STEP 8 trial, with a mean weight loss of 17.1% in the semaglutide group, which was significantly more effective than liraglutide (mean weight loss of 6.6%)

Ratner RE, Dickey R, Fineman M, et al

[DOI] [PubMed] [Google Scholar] 35

Phentermine is a stimulant that suppresses appetite primarily through norepinephrine release