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Lancet1987 Dec 5;2(8571):1300-4

Key Finding: The percentage of US adults taking GLP-1 drugs for weight loss more than doubled between February 2024 (5.8%) and June 2026 (12.4%), according to Gallup research

Genetic predispositions in GLP1R and GIPR pathways may influence baseline appetite sensitivity and metabolic response, but genetics alone do not determine outcome

Information campaigns and price nudges have mixed results at best

As research continues, the list of potential applications grows, suggesting these medications may eventually be viewed less as weight loss drugs and more as metabolic health optimizers with wide-ranging benefits