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2% with dulaglutide and 3% with placebo [67]
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Heart rate increased transiently by ~7 bpm
Interestingly, they also caused significant weight loss, mostly through effects on the brain that help control hunger and fullness. This finding is why they were developed as weight loss medications
N = 933,970) were included as positive control outcomes 55,56
Daily Semaglutide appears to improve ALT levels more effectively than weekly doses [28], whereas weekly doses effectively reduce transaminitis characterized by elevated ACT and ALT levels [49]
