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Key Mechanism: Fiber slows digestion Reaches the colon fermented by gut bacteria Produces compounds that trigger GLP-1 release Two-Phase Effect: Immediate GLP-1 release after eating Second boost (48 hours later) Second Meal Effect Helps: Reduce cravings between meals Improve next-meal appetite control Best Fibers for GLP-1 Fermentable Fibers (Most Effective) Beta-glucans: Oats Barley Rye Seaweed Mushrooms Other Soluble Fibers Apples Pears Legumes: Lentils Chickpeas Peas 2

Mary Claire Haver, MD, FACOG, MSCP is a board-certified Obstetrics and Gynecology specialist, a Menopause Society Certified Practitioner (formerly the North American Menopause Society (NAMS)), a Certified Culinary Medicine Specialist, and a passionate entrepreneur and best-selling author with a focus on womens health

Discover what research shows about GLP-1 medications and endocrine health during weight loss

Explore the safety considerations, gastrointestinal risks, and essential medical discussions for patients managing both type 2 diabetes and inflammatory bowel disease.

A large clinical trial, co-led by researchers at the UNC School of Medicine, has shown that the popular weight-loss drug significantly reduces cardiovascular events in people with type 2 diabetes, pre-existing cardiovascular disease, and/or chronic kidney disease.

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