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Most people experience some weight regain after stopping GLP-1 medications, as hunger hormones return to pre-treatment levels

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Interestingly, higher incidence of diabetic retinopathy (DR) complications was noted in patients taking semaglutide (3.0%) compared to placebo (1.5%) in clinical trials, with greater risk in those with a history of DR [32]

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Diabetes 63 , 12241233 (2014)

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Implications Type 2 diabetes mellitus (T2DM): In T2DM, responsiveness to GIP is often impaired

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Discovery The development of GLP-1 based drugs for obesity did not happen overnight

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[Accessed on 23.11.2014]

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