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Additionally, topiramate can increase the risk of kidney stone formation and affect electrolyte balance, which may be compounded by dehydration from GLP-1 side effects or reduced oral intake

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Pratley (AdventHealth Diabetes Institute, Orlando, USA), the co-chair of the FLOW trial, stated: This is a patient population at high-risk of severe kidney outcomes

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How Thyroidectomy Affects Weight Loss and Metabolism Thyroid hormones (T3 and T4) drive cellular metabolism by influencing mitochondrial function, heat production, and nutrient absorption