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The theoretical concern based on animal data has not materialised in clinical practice

Krieger J-P, Arnold M, Pettersen KG, Lossel P, Langhans W, Lee SJ

Some providers reduce the dose while maintaining daily frequency

Early clinical trials show promising weight loss potential in non-diabetic patients

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It is also worth noting that in obese patients with T2DM, GLP-1RA-mediated weight reduction has been associated with the detection rate of breast cancer [34], with the highest incidence observed in patients who experienced more than 10% weight loss following treatment [35]