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The article reviews the pathophysiology of both pediatric obesity and MASLD, explores current therapeutic strategies, and discusses the emerging role of glucagon-like peptide-1 receptor agonists, such as liraglutide, semaglutide, exenatide, and dulaglutide, in managing obesity, as well as explores current limited pediatric literature on the use of these medications in MASLD

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When considering a possible use of JWU-A021 in therapeutics, it is noteworthy that the TRPA1 channel activator cinnamaldehyde exerts blood glucose-lowering and weight-reducing actions in mice 21
