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The most common effects are gastrointestinal: oily spotting, increased flatulence with oily discharge, loose or urgent stools, and sometimes steatorrhea

Sirtuin 1-Mediated Cellular Metabolic Memory of High Glucose via the LKB1/AMPK/ROS Pathway and Therapeutic Effects of Metformin

Second, vomiting showed a clearer dose-dependent increase, rising from 13.0% at 6 mg to 24.0% at 36 mg

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(2015) Short hydrophobic peptides with cyclic constraints are potent glucagon-like peptide-1 receptor (GLP-1R) agonists
