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The link between GLP-1 and gallbladder problems is real but modest: semaglutide, tirzepatide, and liraglutide raise the risk of gallstones and biliary disease by a small absolute amount, driven mostly by how much weight you lose and how fast, plus a direct slowing of gallbladder emptying

Additionally, it inhibits glucagon release from pancreatic -cells and reduces hepatic glucose production [14]

In addition, 6.1% of Canadian adults have prediabetes, making them highly prone to the development of type 2 diabetes

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