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Do not start a GLP-1 receptor agonist in a patient with a prior diagnosis of gastroparesis

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We have assessed various metabolic parameters after short and long exposure of clonal BRIN-BD11 -cells and rodent islets to the GLP-1R agonist Exendin-4 (50nM)

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Doctors in the US are not clear on what is causing the side effect, but say that it has been linked to rapid weight loss.