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Fatigue is not prominently featured in the adverse event profile reported in tirzepatide's pivotal clinical trials

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[63] It declared the shortage over in October 2024, but enforcement was delayed until the end of 2024, after a lawsuit by compounding pharmacies challenged the declaration

Semaglutide remains partially active during the first few days of the washout period

That said, this comparison is not as simple as tirzepatide wins, use tirzepatide. The full picture is more nuanced, and I want to give you an honest account of both what the data shows and what I actually see in our clinics