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Frankly, after the first year, once a year for very low doses lithium or twice a year for very low dose clozapine would be enough, along with routine labs you do for your primary care exam

Graaf, C

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GLP-1-based therapies offer a pharmacological intervention that targets these mechanisms directly, allowing for more effective management of obesity

Altered CAMKII expression, which regulates orexigenic neuropeptides like NPY, also reflected compensatory adaptation to weight loss (Sanchez-Garrido et al., 2024)