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Conclusion Given the increasing prevalence of upper GI surgeries, the incidence of PH is expected to rise

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In animal studies, GLP-1 agonists triggered anxiety early in treatment which then subsided and shifted toward reduced depression-like behaviour with continued use

Protocol 2 included 81617 initiators of GLP-1 receptor agonists (n=16768) and SGLT-2 inhibitors (n=64849)

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