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However, side effects can sometimes be extreme and cause serious discomfort or other medical problems

While tirzepatide's glucose-dependent mechanism reduces hypoglycemia risk compared to some other diabetes medications, any intervention affecting glucose metabolism warrants monitoring

The results showed that tesofensine, particularly at a dose of 0.5 mg, led to a significant improvement in the total UPDRS score (-4.7 points) and a reduction in off time (-7.1%)

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Assessment should include medication review to identify other constipating agents, digital rectal examination when indicated, and consideration of abdominal imaging if obstruction is suspected

[DOI] [PubMed] [Google Scholar] Patch RJ, Searle LL, Kim AJ, De D, Zhu X, Askari HB, ONeill JC, Abad MC, Rentzeperis D, Liu J, et al