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Description
The initial muscle loss seen with GLP-1 RA treatment as well as the ongoing replacement of muscle with fat with treatment cycles involving treatment interruptions can result in unfavorable changes in body composition in patients with obesity that can have profoundly negative repercussions, and can exacerbate obesity-related metabolic and health concerns 14,15,16
Effect of liraglutide on estimates of lipolysis and lipid oxidation in obese patients with stable coronary artery disease and newly diagnosed type 2 diabetes: a randomized trial
All of these factors work together to help you and your provider decide if a GLP-1 medication could be a safe, helpful tool for your personal weight loss journey
It can take up to 18 months to see the full impact of these medications
Tirzepatide also activates GIP receptors
10:418-429 [PubMed: 35468322] 387
