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In comparison, Wegovy only works on one hormone receptor, while Mounjaro targets two

This type of structured escalation yields far richer data than a single fixed-dose trial would have allowed

Meta-analyses show an overall relative risk increase of about 1.37-fold, with higher risk at higher doses and longer treatment duration

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doi: 10.1074/jbc.M205532200

The absence from this map worth noting is Roche, whose publicly disclosed obesity strategy is concentrated on dual GLP-1/GIP (CT-388) and does not include a triple-agonist deal or disclosed internal program
