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This analysis used a population pharmacokinetic model of semaglutide to identify clinically relevant covariates for exposure

Major cardiovascular outcome trials and real-life observations have proven that glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs), regardless of structural GLP-1 homology, exert clinically relevant cardiovascular protection

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Meta-analysis was conducted using a random-effects model in Stata 17

In conjunction with all the effects, GLP-1 RAs have been found to lower weight and aid in weight management.
