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Description
DLC-1 directly interacts with FBF-2, but not with FBF-1, by binding to several sites outside of FBF-2 RNA-binding domain where FBF-1 and FBF-2 sequences diverge (Wang et al., 2016)
Acta Endocrinologica (Copenhagen) 1963;44:139149
Lancet Diabetes Endocrinol 6(4):275286 Rossing P, Baeres FMM, Bakris G, Bosch-Traberg H, Gislum M, Gough SCL et al (2023) The rationale, design and baseline data of FLOW, a kidney outcomes trial with once-weekly semaglutide in people with type 2 diabetes and chronic kidney disease
No washout when switching
These advancements may lead to a more streamlined treatment experience, potentially increasing the adoption of these therapies among patients
Clinical evidence shows that stopping GLP-1 therapy usually leads to weight regain and worsening blood sugar control
