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Chen H, New P-K, Yang Y et al (2019) A forward chemical genetic screen reveals gut microbiota metabolites that modulate host physiology

1 Excess adiposity is a major contributor to BP elevation, with estimates suggesting that obesity causes 65%-78% of primary hypertension cases

Common side effects (nausea, constipation) typically resolve within 2-3 weeks
Rybelsus can be used alone or with other diabetes medications like Metformin
N Engl J Med (2019) 380(4):34757

By binding with HSA or IgG-Fc, the half-life of protein drugs could be extended
