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Diana Mesa, RDN, LDN, CDCES, founder of En La Mesa Nutrition, agrees, adding that Berberine does have some similarities [to GLP-1 RA medications] in that it can trigger the pancreas to release insulin and helps make cells more sensitive to the effect of insulin, which is a characteristic similar to what Metformin [another prescription medication prescribed to treat type 2 diabetes and other off-label conditions] does. Still, she notes that its unclear whether or not Berberine has any appetite-suppressing effects like Ozempic and similar medications

It is important to note that these side effects are not very common and can often be managed effectively [61, 68,69,70,71]

Additionally, 58% of patients taking the medications for weight loss discontinued use before seeing a clinical benefit

The ATLAS Community Health Initiative is supported by UCLA Health, the David Geffen School of Medicine and a grant from the UCLA Clinical and Translational Science Institute (UL1TR001881)

Preclinical studies suggest that by activating these receptors, GLP-1 agonists may dampen the dopamine surge typically triggered by alcohol consumption, thereby potentially reducing its rewarding properties and decreasing the motivation to drink

Efficacy and safety of glucagon-like peptide-1 receptor agonists in type 2 diabetes: a systematic review and mixed-treatment comparison analysis