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Removing friction can matter as much as the drug itself

Recently, we found that triagonist-induced enhancement of insulin secretion exceeds levels observed with the loose co-administration of the three individual agonists in murine islets [9]

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The study revealed that use of semaglutide was associated with a 42% lower risk of worsening mental illness compared to periods when the same individuals were not taking GLP-1 receptor agonists
In response, the FDA agreed to reassess its position and let compounders continue making the drugs while negotiations proceed

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