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For example, LY3437943 , a novel triple agonist peptide discovered by Eli Lilly that targets the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and GLP-1R (GCGR+GIPR+GLP-1R from the list above), can effectively reduce body weight and improve glycemic control in obese mice

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The study included 17,604 people ages 45 and up from 41 countries and tracked them for at least three years on average

Teplizumab was approved in 2022 and is highlighted in the diabetes guidelines

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