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10.1210/mend-3-6-1014
A person at the lower end of the overweight range may be more sensitive to doses calibrated for someone fifty or a hundred pounds heavier
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Some have linked the problem to an observed drop in testosterone, the male sex hormone, levels recorded among men taking semaglutide
But scientists say that if orforglipron and similar drugs in development reach the market, they could aid efforts to tackle obesity and diabetes, including in LMICs where the prevalence of such conditions is rising rapidly
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