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The early pancreatic-cancer fear has largely not held up in long-term trials and reviews (Jalleh 2026)

Disproportionality analysis A sequential approach was adopted to systematically address major confounders: (1) An exploratory disproportionality approach comparing GLP-1RAs with all other drugs reported in the FAERS database, using venlafaxine as the positive control and empagliflozin/orlistat as the negative control
The need for efficient remedies like GLP-1 therapies is only increasing because of the rise in sedentary lifestyles and poor diets

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