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Corticosteroids can increase appetite and water retention, potentially offsetting GLP-1 medication benefits

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No approved treatments currently exist that target the underlying changes that lead to diabetic cardiomyopathy and its progression to overt heart failure, Januzzi said

however, it is unknown whether the observed improvement in lymphatic function is solely due to weight loss-associated systemic benefits or in synergy with a lymphatic-specific effect of these pharmacological therapies

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